No, never had an issue with Signal backups.

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I bought a laptop that came with a broken charger, I could easily test it myself as a friend also had an HP laptop with the same brick (this was before the days of USB C).

I tried to make a warranty claim and they wanted me to send the laptop too and wipe the HDD, the RMA process would take weeks on top of that.

I ended up buying a 3rd party charger, I’m sure their RMA process is overly long and convoluted to deter people from making warranty claims

I have the following apps backing up to a syncthing share

• Aegis
• OpenScale
• Gadgetbridge
• OpenTracks
• Signal

all of them were set and forget, except for Gadget bridge who would randomly loose access to the shared

The following apps allow to manually backup to a file, but not automatically.

• AntennaPod
• Catima
• Birday
• Tickmate