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That map for the Mason-Dixon Line is not correct. The original line was at that latitude but it ended at modern day West Virginia. It was the line of demarcation between Pennsylvania, Virginia, Delaware and Maryland. It was used in congressional debate during and after the the Missouri Compromise to refer to the line of division between slave states and free states which lead to an unofficial expansion. Since the 1820s it has been understood to move directly north from it’s original endpoint until it hits the Ohio River then to follow the river west to the Mississippi River then to travel along the eastern, northern and western borders of Missouri. It ends on the 36°30’ parallel and extends straight west through the Louisiana Purchase. The 36°30’ line was applicable in the territories but not among the states. The Mason Dixon was the line of separation among the states.
https://history.howstuffworks.com/historical-events/mason-dixon-line.htm
Ohio, Indiana, and Michigan are east of the Mississippi. We couldn’t reliably cross the Appalachian Mountains until shortly before the American Revolution. Expeditions before Daniel Boone forged the Wilderness Road had to go around so the most direct route between NY and where Chicago is now went about halfway down Alabama. The Appalachians were the original western frontier and the Midwest was the Northwest Territories. As the country expanded westward and new territories were established and the Northwest Territories gained statehood they became the Midwest.
There’s a decent amount of industry there, I think that is likely caused by the overlap between the Rust Belt and the Midwest.
I think it probably has to do with the overlap between the Midwest and the rust belt.
Environment affects gene expression so cloning below the cellular level (genetic cloning) results in an individual that does not have the same developmental changes caused by environmental factors that the original had. With current technology genetic cloning has been done and cellular cloning is not possible.
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This isn’t necessarily what the commenter was talking about but wage theft is estimated to be at about $50bil per year which is more than all other forms of property crime combined and it is rarely punished even when reported.
https://www.theguardian.com/us-news/2023/jun/15/wage-theft-us-workers-employees